Wall motion and hemodynamics in intracranial aneurysms

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چکیده

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Intracranial Aneurysms: Connecting Hemodynamics, Biomechanics and Wall Characteristics

Increased detection of incidental unruptured intracranial aneurysms has made the clinical decision making process and management of patients with this disease more challenging since the risk of complications of surgical and endovascular interventions can easily exceed the aneurysms’ natural risk of rupture. On the other hand, because aneurysm rupture and subsequent subarachnoid hemorrhage have ...

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Wall Mechanical Properties and Hemodynamics of Unruptured Intracranial Aneurysms.

BACKGROUND AND PURPOSE Aneurysm progression and rupture is thought to be governed by progressive degradation and weakening of the wall in response to abnormal hemodynamics. Our goal was to investigate the relationship between the intra-aneurysmal hemodynamic conditions and wall mechanical properties in human aneurysms. MATERIALS AND METHODS A total of 8 unruptured aneurysms were analyzed. Com...

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Intracranial aneurysms are a common pathologic condition with a potential severe complication: rupture. Effective treatment options exist, neurosurgical clipping and endovascular techniques, but guidelines for treatment are unclear and focus mainly on patient age, aneurysm size, and localization. New criteria to define the risk of rupture are needed to refine these guidelines. One potential can...

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The genesis, growth and rupture of intracranial aneurysms (IAs) involves physics at the molecular, cellular, blood vessel and organ levels that occurs over time scales ranging from seconds to years. Comprehensive mathematical modelling of IAs therefore requires the description and integration of events across length and time scales that span many orders of magnitude. In this letter we outline a...

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ژورنال

عنوان ژورنال: Journal of Physics: Conference Series

سال: 2013

ISSN: 1742-6588,1742-6596

DOI: 10.1088/1742-6596/477/1/012004